Thanks to its central position, Florence is the most important railway hub in Tuscany. The Cradle of the Renaissance is home to a number of train stations and it is connected to Livorno and Massa via Pisa, to Viareggio via Prato and Lucca, to Siena via Empoli, and to Cortona and Chiusi via Arezzo.
Florence's main train station is Firenze Santa Maria Novella (sometimes shortened in Firenze SMN), set a in the very heart of the city centre, a few hundred metres away from the Duomo. Many tourists often seem confused by Firenze Rifredi, another station in town, but you should know that when you get there, there are still 5 minutes left to reach Santa Maria Novella station. The Firenze Campo di Marte station is also set in a strategic position, especially in case you're staying in the Campo di Marte, Sant'Ambrogio or Santa Croce areas of Florence.