The company that currently carries out the bus connection service between Pisa airport and Florence is the Sky Bus Lines Caronna. The service runs every day, all year round; the duration of the journey is about 60 minutes, traffic permitting, without intermediate stops.
In Pisa, busses depart and arrive in front of the airport. In Florence, the daytime runs stop near the Tramway line T2 stop "Guidoni", the night ones (10/11 p.m. - 6/4 a.m., depending on the season) in front of the central train station of Santa Maria Novella.
For departures from Florence, tickets can only be purchased online. In Pisa, tickets can also be purchased at the dedicated ticket office.
Sky Bus Lines Caronna also connects the airport of Pisa to the airport of Florence via Montecatini, Pistoia and Prato.