From Rapolano Terme follow signs for Serre di Rapolano-Montisi, taking the SP 26 “Asciano-Rapolano: shortly after passing under the railway bridge turn left heading towards Serre di Rapolano. After the town centre and after a steep downwards hill (direction Asciano, a slope of 13%), turn left following signs for Sant’Andreino on the SP 64 “Serre di Rapolano road”. Look out for the travertine quarries on your right, just next to the church of Sant’Andreino (600 m from the intersection).
From here, the road heads gradually downhill to another intersection (500 m). Turn left to continue along the quarry road. After around 2 km you will reach a T-junction: turn right here towards Asciano and after the second level crossing continue to the centre of town or, if you prefer, turn right and take a road with beautiful views to Rapolano Terme (10 km).