The Santissima Annunziata Sanctuary is situated in Vinci along the road to Empoli. The church, near the Conti Guidi Castle, was built in the early 17th century. Following a number of renovations over the course of the centuries, the current structure features a façade with three arches and an adjoining bell tower.
Several frescoes produced by Paolo Bernardino del Signoraccio, more commonly known as Fra Paolino da Pistoia, can be found inside the church. The artist’s training was influenced greatly by Perugino, even though the experiences that affected the Pistoia-born artist’s learning most of all, are associated with the painting he conducted in the workshop of San Marco in Florence, under the guidance of Fra Bartolomeo. The artist’s most important artwork, the Annunciation, is set above the altar of the church.