The work is characteristic of Giotto’s style: the concreteness of the figures, particularly that of Christ, who seems ‘weighed down’ by death, his muscles tense and stomach sagging. By comparing this work with the artist’s other paintings, and especially his other crucifixes, scholars suspect Giotto may have painted the Santa Maria Novella crucifix in his early years. On the other hand, the iconography is perhaps the most interesting aspect of this artwork. With this cross, Giotto modified the 13th-century model of the Dying Christ on the Cross, exemplified in the artworks of Cimabue and Giunta Pisano.
In the works of his predecessors, the bi-dimensional figure of Christ is much more slumped on the cross and the two nails at Christ’s feet are different. Giotto changed this model, after he saw the change in sculptures by Nicola and Giovanni Pisano. In Giotto’s new model of the Dying Christ, he overlapped Christ’s feet, making this the point in which Christ’s physical and moral sufferance converges. He also included the trilingual inscription (in Greek, Hebrew and Latin) at the top of the cross. On the extremities of the arms of the cross, he painted the Virgin Mary and Saint John. At Christ’s feet, there is the image of the hill of Calvary and the skull of Adam.