This masterful altarpiece shows the Provost of Prato, Germiniano Inghirami, patron and purchaser of many frescoes, such as those in the Cappella Maggiore di Santo Stefano. The altarpiece was commissioned around the year 1455 to decorate the altar of the church of Santo Stefano, or Prato Cathedral.
Inghirami is shown in the painting in the foreground, kneeling before the platform holding Saint Jerome in the centre of the painting. The saint is swathed in rich red cloth. Next to him is a disabled person who has been healed, a direct reference to the cripple painted by Masaccio in the scene showing San Pietro in the Brancacci chapel.
The altarpiece also shows a group of monks in movement who form a crown around the body of the saint which lays on a rich cloth. This cloth, interwoven with pomegranates, is also used in another work of art by Desiderio da Settignano. In the upper part of the altarpiece is a group of angels. Here it’s possible to recognise the hand of Fra Diamante. Underneath the angels there are scenes from the life of the saint which were painted by members of the artist’s workshop. This painting stands out for its use and range of chromatic colours. The varying shades of grey represent the emotional tone and pain of the people in the painting.